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PGE 2 was determined using a prostaglandin E 2 assay kit (H099-1, Nanjing Jiancheng Biotechnology Co., Ltd., China) ( Cell viability The control group was treated with 100 l of RPMI-1640 complete medium, and the experimental group was treated with 100 l of LPS (1.0 ng/ml), 100 l of IAP (40 U/ml), and 50 l IAP (4/20/40/80 U/ml) + 50 l LPS (2.0 ng/ml)

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Artif Cells Nanomed Biotechnol 42:612

In parallel, resveratrol markedly reduces neuroinflammation in toxin models: studies report that resveratrol-treated PD model animals have lower levels of pro-inflammatory mediators such as COX-2, TNF-, and IL-1 in the nigrostriatal system, as well as reduced ROS accumulation (47)