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A recent study aimed at utilizing pre-activated thiol groups to facilitate better stability, prolong retention time of dosage forms, offer mucoadhesion in order to enhance uptake and oral bioavailability (Iqbal et al., 2012)

If nothing else, that should give you some indication of how important it is

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184,185,186 The role of the SASP in tumors can be summarized as follows: (1) It promotes the growth and proliferation of tumor cells