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Compared with placebo, the tested formulation produced a more pronounced reduction in thigh circumference and in fat mass as measured by dual-energy X-ray absorptiometry

Based on this knowledge, utilizing a mitochondria-targeted curcumin drug as TDC helps achieve better advantages of curcumin

doi: 10.1016/j.fct.2024.114851 96

1 The TFCC physically separates the distal radioulnar joint (DRUJ) from the radiocarpal joint

Another study also implicated SIRT4 in regulation of leucine catabolism indicating that BCKDH is likely an additional target of this regulation (74)