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In cirrhosis, CB1 receptors are upregulated and expressed in fibrogenic liver cells, and CB1 inhibition has been linked to reduced fibrosis and lower TGF- signaling

Finally, prebiotics might be implicated in diminishing adipogenesis, via inhibiting the endocannabinoid system in the gut and adipose tissue (60, 66)

Human and host sequences from the samples were removed by comparing metagenomic reads against human (GCF_000001405.40) and mouse (GCF_000001635.27) reference genomes using the Bowtie2 tool [11]

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timonensis , that possess the polypeptide(s) required to promote the BBTMA metabolic transformation