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In hereditary or acquired metabolic defects, an initial intravenous bolus of 50 mg/kg may be administered over two to three minutes, followed by maintenance doses of 50 mg/kg every six hours or continuous infusion to achieve a total daily exposure of up to 300 mg/kg in critical illness

in fact, poor tolerability was encountered in only 3.9% of patients, whereas 1.6% discontinued treatment due to treatment-related adverse events [46]

doi:10.1016/S2666-5247(23)00221-5

The association of muscle carnitine levels and acyl-CoA oxidation is the basis of a multi-million energy and weight loss nutraceutical industry

This reaction is a rate-controlling step for the -oxidation of fatty acid (13)

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