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Key Safety Differentiators No IGF-1 elevation: AOD-9604 does not stimulate IGF-1, meaning it avoids risks such as organ/tissue overgrowth or acromegaly No glucose disruption: Clinical data shows it does not impair insulin sensitivity or worsen blood sugar regulation Comparable to placebo: In obesity trials, the incidence of adverse effects was similar to placebo groups, underscoring its tolerability Legal Status of AOD-9604 United States: AOD-9604 is not FDA-approved as a drug, dietary supplement, or weight loss therapy

Statistically non-significant, clinically uninteresting

Expired vitamin solutions may have reduced potency and an increased chance of contamination or chemical breakdown

[DOI] [PMC free article] [PubMed] [Google Scholar] 100.Roepcke S, Plock N, Yuan J, Fedyk ER, Lahu G, Zhao L, et al

Research shows that low serum vitamin B-12 levels are linked to decreased bone density, which can lead to fragile bones and a higher risk of osteoporosis