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Glutathione levels also are lower and oxidative stress is higher in conditions associated with mitochondrial dysfunction, including ageing, HIV infection, diabetes, neurodegenerative disorders, cardiovascular disorders, neurometabolic diseases, cancer, obesity and other conditions

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Moreover, in a mouse model without elevated alanine aminotransferase (ALT), the elevated serum miR-122 levels were positively associated with the severity of MASLD (103)