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In normal conditions, the loading conditions activate the Piezo1 channel in bone marrow mesenchymal stem cells, which leads to the repression of the Ccl2-Lcn2 inflammatory cascade and a tendency toward osteogenesis instead of adipogenesis (290)

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In addition, CoQ10 reduces the mRNA expression of HSD11B1 and FKBP5 in immature oocytes, as well as in cumulus cells regarding HSD11B1