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doi: 10.3389/fphar.2025.1617546 Received 24 April 2025 Accepted 21 July 2025 Published 31 July 2025 Volume 16 - 2025 Edited by Izolde Bouloukaki, University of Crete, Greece Reviewed by Maimaiti Tuniyazi, Jilin University, China zhiqiang Dou, Changchun University of Chinese Medicine, China Xue Wan, Mayo Clinic, United States Updates Copyright 2025 Lv, Zhang, Liu, Wang and Zhao

Leaky gut syndrome , irritable bowel syndrome (IBS) , and Crohns disease are chronic conditions marked by inflammation and damage to the intestinal lining

The mean age ranged from 44.9 to 57 years

When cells are subjected to high temperature or other environmental stress, the expression of HSPs is upregulated to prevent cell damage and death

Frequent communication is important among the prescriber, other members of the healthcare team, the patient, and the caregiver/family during periods of changing analgesic requirements, including initial titration

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