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Lower respiratory infections, pneumonia, bronchitis, tuberculosis, pharyngitis, laryngitis, and the common cold, as well as obstructive lung disorders, such as asthma, chronic obstructive pulmonary disease (COPD), and lung cancer, are among the most prevalent respiratory diseases

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Pitolisant's efficacy could be mediated through its activity that increases the synthesis and release of histamine in the brain via competitive binding to presynaptic histamine-3 autoreceptors

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