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In this regard, several studies demonstrated that overexposure to stress hormones could alter the niche, metabolism, and functioning of the SPCs of the stress system, resulting in increased differentiation and reduced numbers of these cells

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To detect LYSET, M6P (scFv M6P), GNPT3HA KI, or the uninduced 10xGCN4, the anti-protein A HRP (PA00-03, Rockland, for LYSET and M6P) or mouse HRP (115-035-046, Jackson labs, for GNPT3HA KI) secondary antibodies were used at 1:10,000 dilution

TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling