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Description
Medicina (Kaunas, Lithuania), 60(1), 50
a) Loperamide (Imodium) OTC, most commonly used Acts on -opioid receptors in gut Does not cross BBB no CNS effects b) Diphenoxylate + Atropine (Lomotil) Diphenoxylate slows motility Atropine added to prevent abuse High doses CNS effects Uses: Non-infectious diarrhea (e.g., IBS, travelers diarrhea) Avoid in: Bloody diarrhea, C

Youmans et al., 2012

For tirzepatide to meet cost-effectiveness standards, its price must be reduced by over 30%, while semaglutides price needs an 82% cut

doi: 10.1001/archneurol.2010.225 91 KochkinaEGPlesnevaSAVasilevDSZhuravinIATurnerAJNalivaevaNN

These include nasal inhalation delivery for non-invasive brain therapy for rescue therapy of acute migraine attacks, rescue therapy for heroin and opioid overdose, and neurodegenerative diseases such as Alzheimers
