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[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Martens CR, Denman BA, Mazzo MR, et al

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This suppression reduces production of pro-inflammatory cytokines including TNF-alpha, IL-6, and IL-1, creating an environment more conducive to tissue repair

KPV downregulates inflammatory signaling including NF-kB in preclinical models, which is the basis for interest in inflammatory skin conditions

Moreover, some marine organisms can serve as safe collagen source since it is abundant in nature which can be broken down into small different proteins with various biological activities

This is slower than popping an ibuprofen, but peptides actually heal the damaged tissue causing pain rather than just masking symptoms