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Animal model studies indicate that such vesicles localize to astrocytic endfeet and impair glutamate uptake by modulating EAAT2 function, indicating a possible contribution to excitotoxic stress [28]

These cells have one or two long (up to 1 mm in length) processes that penetrate into superficial cortical layers (1248)

The composite microneedle patch, consisting of 100 dissolvable microneedles with drug-loaded tips and a backing layer, has been designed to improve the oral transmucosal drug delivery efficiency (43)

Porto B

Zhang J, Chen H, Chen C, Liu H, He Y, Zhao J, Yang P, Mao Q, Xia H

In any of these cases, the safest course is to discard the vial and start fresh