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Nephrotoxicity and neurotoxicity of polymyxins Therapies involving PMs are associated with significant adverse effects, most notably nephrotoxicity and neurotoxicity

J.PetrosinoJ

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Co-Detection by indEXing (CODEX) staining and imaging of the mice kidneys Barcode-conjugated antibody staining of tissue sections mounted on polylysine-coated cover slips was performed using a commercially available CODEX Staining Kit with fresh frozen tissue using a Akoya CODEX instrument (Akoya Biosciences, Marlborough, MA, USA) with a Keyence BZ-X800 microscope plus Nikon PlanApo NA 0.75 objective (Nikon, Tokyo, Japan)

Journal of Biological Chemistry 279:3286932881