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GS mRNA levels changed in parallel to that of GCLC in all three conditions while GCLM mRNA levels were unchanged [26,51,142]

Cloughtery, D.Y

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The observed inhibitory effects of G6PD knockdown on these cellular behaviors suggest that targeting G6PD could represent a promising therapeutic strategy

These compounds act by scavenging reactive oxygen species and inducing endogenous antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GPx) [9]

Stress Management: Chronic stress increases the demand for antioxidants, meaning you may "burn through" your supply faster than you can replenish it