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Both compounds do not cross the blood-brain-barrier (BBB), although paclitaxel is accumulated in dorsal root ganglion neuronswhich lie outside the BBBvia largely unknown mechanisms (Cavaletti et al., 1997, 2000

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Conversely, the 3.0 g/d group displayed 4.3% and 6.0% lower values of PP with the 4 th and 5 th sprint and the PP was up to 4.7% lower with the 4.5 g/d dosage

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