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These muscle disabilities were induced by different peripheral causes (e.g., direct muscle, tendon, ligament, and nerve injury [80,81,82,83,84,85,86,87,88,89,90,91], succinylcholine [227], vascular occlusion [228], over-dose of potassium, magnesium or lithium [138,216,229], and tumor cachexia [22])

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Maintaining an adequate GSH redox status and 25-hydroxy-vitamin D levels will have the potential to reduce oxidative stress, enhance immunity and diminish the adverse clinical consequences of COVID-19 especially in African American communities having glucose-6-phosphate dehydrogenase deficiency, enzyme necessary to prevent GSH exhaustion and depletion (Jain and Parsanathan, 2020

Activation of Nrf2/HO-1 signaling: an important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress

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FIGURE 1 ASD results from a complex interplay between genetic and environmental factors