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In vivo pharmacokinetics, conducted in Sprague-Dawley rats, showed sustained PX plasma levels over two weeks, with a maximum plasma concentration of 19.06 4.73 ng/mL observed at 48 0.25 h

We also analyzed changes in nuclear factor B (NF-B) and cyclooxygenase-2 (COX-2) expression levels to delineate possible mechanisms of their combined action

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doi: 10.3390/nu14245209

RNA extraction and RT-PCR for gene expression analysis To determine the effect of HT stress on the transcription levels of Calvin cycle enzyme genes and antioxidant enzyme genes and their changes after GSH application, we tested photosynthetic genes including those encoding ribulose-1,5-bisphosphate carboxylase/oxygenase activase ( RCA ), RBCL and RBCS involved in CO 2 fixation
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