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It was not long thereafter that the first reports describing serious complications were published, and for this reason, implants had to be removed, leaving some patients almost blind (Hoguet et al., 2012

Z-D-Phe-Arg(HCl)-Trp-Lys( Boc)-NH 2 ( 7 ) 2 A solution of HCl in dioxane (17%, 50.3 mL as calculated from the acid-base titration of product 6 obtained from the previous step) was added dropwise to a stirred solution of protected dipeptide 6 (134.5 g, 295.3 mmol) in DMF (800 mL) at 7 C

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Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma

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