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Neuron 112 , 19111929 (2024)

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Furthermore, our study revealed that Tibetan M9a+sh EPAS1 cells exhibited the most robust mitochondrial function, supporting the hypothesis of increased oxygen transport and utilization capacity in Tibetans [36, 37]

Grabherr F, Myer M, SchmitZ JJ, Schwrzler J, Mayr L, Philipp M et al

doi: 10.1016/j.neuroscience.2011.01.005

Necrotic death leads to the leakage of intracellular oxidative and inflammatory components, which then propagate more inflammation, oxidative stress, and death in neighboring cells (Figure 5) (173)
