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Neurological symptoms often develop gradually and may include: Paraesthesia : tingling or 'pins and needles' sensations, typically starting in the feet and hands Numbness : reduced sensation in the extremities, which may affect balance and coordination Burning pain : particularly in the feet, often worse at night Weakness : muscle weakness and difficulty walking Balance problems : unsteady gait and increased fall risk due to proprioceptive impairment Cognitive changes : memory problems, confusion, difficulty concentrating, and mood disturbances Haematological signs may accompany neurological symptoms and include fatigue, weakness, pallor, and shortness of breath due to megaloblastic anaemia

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High-throughput computing leverages parallel processing to rapidly analyze large datasets, facilitating the identification of nanostructures with enhanced catalytic performance, and accelerating material screening while reducing experimental trial-and-error 220

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[DOI] [PMC free article] [PubMed] [Google Scholar] 1814.Verkhratsky A, Orkand RK, Kettenmann H
