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The aggregation of mutant ATXN3 proteins in vivo was associated to interrupted synaptic transmission

[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Smoday I.M., Petrovic I., Kalogjera L., Vranes H., Zizek H., Krezic I., Gojkovic S., Skorak I., Hriberski K., Brizic I., et al

Description AOD9604 AOD-9604 5mg (Lyophilized Peptide) For Research Use Only AOD-9604 is a modified fragment of human growth hormone (HGH), specifically amino acids 176191 , developed for its potential role in fat metabolism and lipolysis research

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The mechanisms studied in animal models include growing new blood vessels (angiogenesis, via VEGFR2), helping repair cells move to the injury (fibroblast migration, via the FAK-paxillin pathway), and supporting blood flow through the nitric-oxide pathway