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One study examined BPC-157 in a pulmonary hypertension model

& Tababe, M

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Apr 15 2011b;117(8):1775-1782

Similarly, defects in CMA led to reduced lipid metabolism, impaired clotting function, decreased VSMC resistance to lipid toxicity and increased dedifferentiation processes in mice, thereby further elevating the risk of atherosclerosis (199)

Notably, altering the Lys-PG level did not affect the AcvB membrane association, suggesting that Lys-PG itself did not directly regulate AcvB membrane binding
