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Circadian Rhythm Regulation and Melatonin Production Epithalon exerts significant regulatory effects on pineal gland function and circadian rhythm homeostasis, particularly in restoring age-related declines in melatonin synthesis

Two robust regression LME models (package(nlme)(Pinheiro et al., 2023)) were estimated for each brain region to investigate the relationship between metabolite (GSH or GABA+) levels and diagnosis group, age, and sex, accounting for the random intercept of each participant

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