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They found that at the dose of 0.2% for 6 weeks, CPZ could induce complete demyelination in the corpus callosum while having no detectable toxic effect on the peripheral organs such as the liver and causing only mild weight loss in the mice

Patients may need approximately 20 to 30 units per side , or about 40 to 60 total units

[DOI] [PubMed] [Google Scholar] 103.Saretzki G., von Zglinicki T

This mouse model of DYT11 dystonia most accurately reflects symptoms seen in patients with myoclonus dystonia, as compared to other rodent models of dystonia

Thangaraj, S

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