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Subcutaneous administration achieves 7085% bioavailability compared to 4050% for oral routes due to hepatic first-pass metabolism

Sculptra is very rarely used in the chin for augmentation, but both Sculptra and Radiesse can theoretically be at least partially dissolved, though its less of a guarantee than an HA filler and generally a slower process

[4] Xu G, Lv ZW, Feng Y, Tang WZ, Xu GX

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