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score 3: more than 50% irregular vascularization: increased number of capillaries, groups of thick-walled blood vessels irregularly arranged in the hypercellular tendon, and a nodular proliferation of blood vessels that can also be vertically directed in relation to their counterpart fibers

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Furthermore, immediately reacts with to generate cytotoxic peroxynitrite (ONOO ) and this reaction itself has several consequences

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Acknowledgements We thank Junko Sato and Mayumi Suda and the Biomedical Research Unit of Tohoku University Hospital for technical assistance with the experiments

Describes the possible importance of dopamine-derived isoquinolines in Parkinson's disease