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Cellular GSH depletion often occurs because of the downregulation of expression or a decrease in the specific activities of the first biosynthetic enzyme GCL 14

Since T315I-Bcr-Abl-transformed 32D cells took longer time to develop leukemia phenotype than WT Bcr-Abl cells, we transplanted 2-fold more cells into C3H/HeNCrNarl mice

36 This phenomenon was first observed in mast cells and results from Fc epsilon receptor I (FcRI) stimulation, causing a transient, transcription-independent increase in intracellular zinc

Ice crystal formation during freezing can disrupt the tertiary protein structure, potentially reducing potency

doi: 10.1007/978-3-319-28383-8_12

Both autism and ADHD impose significant fiscal burdens on society and impact the well-being of affected individuals