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This finding suggests that GSH supplementation may help to shift the balance towards a more reduced environment, potentially protecting against oxidative damage
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Another interesting class of carbon atoms that may serve as deuterium traps are the bis-allylic carbon atoms, notably present in both microbial breakdown products of haem and in polyunsaturated fatty acids (PUFAs)

Here we show, by high resolution structure analyses of enterovirus F3, that reduced glutathione binds to the same interprotomer pocket as the benzene-sulfonamide derivative

[DOI] [PMC free article] [PubMed] [Google Scholar] 179.Buhling K., Schumacher A., Eulenburg C.Z., Laakmann E