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Given its multifunctional nature, it is unsurprising that dysregulation of p62 in cancer cells can promote their growth by several mechanisms including through selective autophagy (Umemura et al., 2016

Astaxanthin is renowned for its potent antioxidant and anti-inflammatory properties

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Transcriptome profiling of advanced stage lipedema patients confirmed mitochondrial and metabolic disfunctions and highlighted Sirtuin signaling alteration Together with DNA methylation profile, transcriptome reprogramming has emerged to have a significant on impact cellular behaviour and to contribute to disease development or progression

The TaWRKY13TaNHX2 pathway positively regulates cadmium tolerance by inhibiting the expression of TaHMA2

Additionally, flavonoids suppress SREBP-1c-driven lipogenesis and enhance PPAR--mediated -oxidation, thereby alleviating hepatic lipid accumulation (Liu et al., 2021b)