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Calicheamicin, a naturally occurring enediyne antibiotic, exerts a potent DNA-damaging effect by binding to the minor groove of DNA, resulting in double-strand breaks and subsequent apoptosis [168]

In a subsequent study, the authors failed to identify diabetes-induced alterations of the neurochemical profile in the cerebellum [24]

Lancet 1969

This tripeptide is made up of three amino acids: glycine, cysteine and glutamate

astrocytes take up GLu via surface receptors to attenuate excitotoxic damage [42].Cytokines stimulate the activation of astrocytes into reactive astrocytic cells (RACs), which proliferate in large numbers