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Skin lightening was noticed in a patient as a side effect of large doses of glutathione, which was given for some other disease, and then onwards, it became more popular as a skin lightening agent
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(2025), "Rationale, Design, and Baseline Characteristics of the TRANSCEND-CKD trial of Retatrutide in Patients with Chronic Kidney Disease," Nephrology Dialysis Transplantation [PubMed]
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