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Re-testing every 3-6 months during ongoing therapy confirms sustained response and detects changes requiring protocol adjustment

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In a study with osteoarthritis patients (see section 5.2 Distribution into blood cells), steady state serum concentrations were determined after intake of 200 mg Pycnogenol per day (34)

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The slides were mounted with a solution containing DAPI (Molecular Probes) and imaged using a Leica TCS SP8 laser scanning confocal microscope (Leica Microsystems CMS GmbH, Wetzlar, Germany)

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[DOI] [PMC free article] [PubMed] 244.Sies H, Jones DP

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