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Additionally, two small studies in participants presenting with antiretroviral-induced neuropathy found significant reduction in subjects' mean pain intensity with oral ALCAR (1-3 g/day) for 4 to 24 weeks, but no effect on objective neurophysiological parameters was found (82, 83)

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We examined plasma catecholamines by ELISA, which is also one of the risk factors contribute to LVR (Supplementary Figure 6D)

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