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10.1038/s41586-018-0620-2 152 VatanenT.De BeaufortC.MarcovecchioM

Mechanistically, we identified a defining characteristic of tumors harboring moderate mtDNA mutations: the early and sustained activation of ribosomal pathways, which we designate as a ribosomal storm and propose as a compensatory adaptive response

PMID: 30565931 Mater Today Chem2024 Jun 1;38:102052 Anal ChemImaging of Mitophagy Enabled by an Acidity-Reporting Probe Anchored on the Mitochondrial Inner Membrane

Apoptosis 29, 967980

The result is a program that integrates the peptide appropriately and sets realistic expectations about what the current research does and does not show

This is important because free radicals are dangerous unstable molecules that are triggered by external factors, like excessive UV exposure and sunburn, pollution, smoking, and ultra-processed foods
