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Read Full Article Here Nicola Traverso et al (2013)

Acyl-CoA synthetase long-chain familymember 4 (ACSL4) catalyzes the conversion of AA or AdA to AA-CoA and AdA-CoA [27]

Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease

ROS also impair proteasome and mitochondrial function

The detoxification reactions comprise the first four steps of mercapturic acid synthesis, [19] with the conjugation to GSH serving to make the substrates more soluble and allowing them to be removed from the cell by transporters such as multidrug resistance-associated protein 1 (MRP1)

Ethics statement The studies involving human participants were reviewed and approved by Institutional Review Board at Nova Southeastern University in Fort Lauderdale, FL, USA