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*Correspondence: Jan Tack [email protected] This article was submitted to Psychosomatic Medicine, a section of the journal Frontiers in Psychiatry Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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While both compounds demonstrate remarkable individual efficacy and work through complementary mechanisms that theoretically could synergize, the complete absence of clinical trial data makes any combination approach purely experimental