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High-dose quercetin (50 mg/kg) showed marked improvement in renal architecture, with nearly normal glomeruli and minimal tubular damage

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In a recent study Winterbourn and colleagues observed that H 2 O 2 rapidly oxidizes the active-site cysteine of mammalian glyceraldehyde-3-phosphate dehydrogenase (GAPDH), specifically when solution levels of carbon dioxide are high

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