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Prog Neurobiol

Available at: Hurley ET, et al

Tepotinib is an effective and highly selective c-Met inhibitor, and its c-Met selectivity exceeds that of most kinase inhibitors with a cell-based 50% inhibitory concentration (IC50) of 1.7 nM ( Capmatinib (INC280) is a highly selective c-Met inhibitor who has an IC50 of 0.13 nM for c-Met (Qin et al., 2019)

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(1992) Effect of increasing doses of recombinant human insulin-like growth factor-I on glucose, lipid, and leucine metabolism in man

The intensity of protein level was quantified by densitometry (software: Image Lab, Bio-Rad)