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Description
It modulates metabolic pathways, including pyruvate dehydrogenase activity, proteolysis, and protein synthesis, while also having anti-inflammatory and antioxidant characteristics
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10.1038/ncb2717 115 MuramatsuH.MatsuoH.OkadaN.UedaM.YamamotoH.KatoS.et al (2013)
It revealed that in the control group, no lipid droplets were observed within hepatocytes, while almost all hepatocytes in the Pg group exhibited varying sizes of bright red lipid droplets
S1P signaling has been implicated in lipid-induced macrophage activation and HSC transdifferentiation
Increased levels of reactive oxygen species also contribute to the formation of AGEs (Brownlee 2001)
