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Conclusion Our study identifies PS-NPs as novel lithogenic cofactors that promote CaOx nucleation, enhance crystal adhesion to renal tubular epithelial cells, and amplify inflammation and ferroptosis through LRP6 downregulation

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Finger prick was employed to evaluate the postprandial glucose response of snack products while venous blood was evaluated for antioxidant enzymes, carbohydrate-hydrolyzing activities, and insulin using standard methods