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Reactive oxygen species can oxidize and directly enhance CaMKII activity, which in turn phosphorylates and activates several Ca 2+ -handling proteins such as the cardiac ryanodine receptor RyR2 or cardiac SERCA (50)

Arora N, Avula H, Avula JK

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Gallelli CA, Calcagnini S, Romano A, Koczwara JB, de Ceglia M, Dante D, et al

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