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Mateos M-V, Blad J, Bringhen S, Ocio EM, Efebera Y, Pour L, Gay F, Sonneveld P, Gullbo J et al (2020) Melflufen: a peptidedrug conjugate for the treatment of multiple myeloma

People with MTHFR mutations should avoid folic acid (the synthetic form) and instead opt for methylfolate, the active, bioavailable version

I also read that damage to/poor liver function is often not factored in for the "older" patient

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It primarily addresses excessive pigmentation
