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This layer releases intrinsic factor that helps the stomach to absorb vitamin B12 from food

Biomarkers of cobalamin (vitamin B 12 ) status in the epidemiologic setting: a critical overview of context, applications, and performance characteristics of cobalamin, methylmalonic acid, and holotranscobalamin II

Oral supplements exist, sure

For purposes of B12 injections, It is manufactured in a laboratory and used to treat or alleviate anemia caused by B12 vitamin deficiency

For females, it could be a result of vaginal discharge

After an injection, as much B12 as possible is captured by the transport protein in the blood (Transcobalamin II) and delivered to the cells