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However, most ferroptosis-related drugs for breast cancer are still in the preclinical stage ( Formononetin, an isoflavone compound derived from a variety of medicinal plants and herbs such as including Trifolium pratense and Astragalus membranaceus , has been identified as exhibiting anticancer potential against various cancer types, such as cervical, head and neck, colon, breast and ovarian cancers ( via the inhibition of Akt activity (Zhou et al., 2019), indicating its potential as a therapeutic agent for breast cancer inhibition

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[DOI] [PMC free article] [PubMed] [Google Scholar] 97.Luong HX, Thanh TT, Tran TH

81,82 A meta-analysis of 15 studies with a total of 7,466 men found genetic mutations (commonly known as single nucleotide polymorphisms or SNPs [pronounced snips]) affecting the methylenetetrahydrofolate reductase (MTHFR) gene that regulates folate metabolism were associated with an increased risk of male infertility