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(2022) highlighted that both probiotic and prebiotic therapies have shown promising results in treating DED
elegans, with a more pronounced effect in neurons (Jeong et al., 2023)
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Some residues in the SH2 domain also suppresses the CSK kinase activity, but the suppression is removed by the binding of the SH2 domain to its ligand ( 3 CSK family members In addition to CSK, CSK homologous kinase (CHK) plays a similar role in phosphorylating Y530 and inactivating Src
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