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Description
Fatty acid molecules that contain a single carboncarbon double bond
Ferroptosis is involved in the progression of hepatocellular carcinoma through the circ0097009/miR-1261/SLC7A11 axis

ART was detected to promote the accumulation of iron regulatory protein (IRP2) by inhibiting its ubiquitination, thus inducing an increase in iron content, generating a large amount of ROS and leading to the onset of ferroptosis of HSCs (96)

doi: 10.1177/0748233712462444

10.1016/j.tiv.2014.02.004 62 KimC.JeongS
This discovery reframed the entire field
