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Akshaya, S., Rowlo, P

This vicious cycle of oxidative stress and neuroinflammation can contribute to the progression of neurodegenerative diseases such as Parkinson's disease [24]

The accumulation of AGEs in the body irreversibly modifies the structure and function of proteins such as collagen and elastin

Repeated weight cycling in obese mice causes increased appetite and glucose intolerance

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Glutamine-derived aspartate induced by GOT2 is transported into the cytosol and converted by GOT1 to oxaloacetate, then converted by malate dehydrogenase (MDH1) into malate and subsequently oxidized into pyruvate by ME1 to create NADPH