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In the past few years, the development of these models has provided preclinical researchers with several options for reducing the number of NHPs used in the drug development process

Retrograde Labeling of Spinal Motoneurons In the experiments studying neuronal survival (n = 23), tibial motoneurons in the L4L6 spinal segments [26], [27] were labeled with non-toxic retrograde fluorescent tracer Fast Blue (FB, EMS-Chemie GmbH, Germany) one week before L5 spinal cord injury

Variations in the induced denaturation parameters can also be explored including, excessive shaking and a lower temperature profile over an extended time period

p53 as a dichotomous regulator of liver disease: the dose makes the medicine

For example, evidence suggests that relapse of depression is observably less frequent when CBT (cognitive behavioral therapy) has been utilized

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